Today, we are excited to announce our US$45
million Series B financing co-led by Kurma Partners and Angelini Ventures, with significant participation
from existing investors EDBI Pte Ltd, ClavystBio, and Boehringer Ingelheim Venture Fund, alongside HighLight Capital and SEEDS Capital. We are also
pleased to welcome Amanda
Gett-Chaperot, PhD (Kurma Partners) and Elia
Stupka, PhD (Angelini Ventures) to our Board of Directors. This new
investment will support our first-in-human, open-label, multicenter, ascending
single-dose Phase 1/2 clinical trial of NVC-001 in patients with LMNA-related
dilated cardiomyopathy (LMNA DCM), with clinical trial sites across the U.S.
and Europe. LMNA DCM is a genetic heart condition caused by mutations in the
LMNA gene, leading to the weakening and enlargement of the heart muscle,
ultimately resulting in a rapid progression toward end-stage heart failure.
LMNA DCM is estimated to affect more than 100,000 patients in the U.S. and
Europe. We are also excited to establish an office in Paris, France, to support
clinical development and bring Singapore innovation to patients globally.